Component resolved diagnosis: when should it be used?

Component resolved diagnosis: when should it be used?

The knowledge on molecular allergy diagnosis is continuously evolving. It is now time for the clinician to integrate this knowledge and use it when needed to improve the accuracy of diagnosis and thus provide more precise therapeutic and avoidance measures. This review does not intend to comprehensively analyze all the available allergen molecules, but to provide some practical clues on use and...

Tigecycline: what is it, and where should it be used?

Tigecycline is the first glycylcycline to be launched and is one of the very few new antimicrobials with activity against Gram-negative bacteria. It evades acquired efflux and target-mediated resistance to classical tetracyclines, but not chromosomal efflux in Proteeae and Pseudomonas. Cmax+ is low, but tissue penetration is excellent and the compound has shown equivalence to imipenem/cilastati...

Role of nocturnal oxygen therapy in obstructive sleep apnea. When should it be used?

The pulmonary artery catheter: when and why it should be used.

The pulmonary artery catheter (PAC) has been in widespread clinical use for 20 yr. It has been modified to allow measurement of cardiac output (CO), mixed venous oxygen saturation (Sf, O2), right ventficular ejection fraction (RVEF) and temporary pacing. The indications for insertion of a PAC have multiplied with time, as has the controversy over the contribution (or lack thereof) of the PAC to...

Component resolved diagnosis (CRD): how much is it presently used by Italian allergists?

Component resolved diagnosis (CRD) represents an innovative and revolutionary tool in allergy diagnosis. At the same time, some criticisms can be outlined. The present web survey aimed at investigating the role of CRD in daily clinical practice, according to a sample of Italian specialists who manage allergic patients. 127 physicians, mostly allergists, completed the questionnaire, mainly comin...